BT1 - Misconceptions 2021

A genetic test cross ALWAYS involves the crossing with an homozygous recessive individual.

• True

• False

In a condition involving X-linked dominant inheritance, the following trend is true:

• Affected mother will always have affected sons

• Affected mother will always have affected daughters

• Affected father will always have affected sons

• Affected father will always have affected daughters

How are fragments of DNA were visualised after gel electrophoresis?

• Ethidium bromide staining + UV light

• Ethidium bromide staining + X-rays

• Tracking dye + UV light

• Tracking dye + X-rays

Ethidium bromide intercalates ____DNA double helix.

• at anywhere on the

• inside the

• between the base-pairs of

• between hydrogen bonds of base-pairs of

Which statement/s describe/s the process for differentiation of stem cells? [Select all that apply]

• toti / pluri / multi-potency

• nucleus contains complete genome

• influence of signals from environment

• change in gene expression, specific for different cell types

Which of the following is/are specialised cells? [Select all that apply]

• Red blood cells

• Platelets

• Lymphoid stem cell

• Phagocytes

• Myeloid stem cell

Telomerase restores the length of telomeres of chromosomes, thus preventing the end-replication problem.

• True

• False

With activation of telomerase gene, induced pluripotent stem cells (iPS) gain self-renewal ability & thus ______.

• can now divide indefinitely

• will undergo uncontrolled cell divisions

Tumour suppressor gene code for proteins that ___. [Select all that apply]

• Arrest / stop cell division

• Promote cell repair

• Promote DNA repair

• Promote apoptosis / cell death

p53 protein is able to directly arrest cell division, promote DNA repair and promote apoptosis.

• True

• False