The main mechanism of dna reparations. Mobile genes and tran

Which of the following DNA repair mechanism is known as the 'cut and patch mechanism'?

• Photoreactivation

• Nucleotide excision repair

• Base excision repair

• Mismatch repair

DNA helicase enzyme involved in base excision repair mechanism is

• DNA helicase I

• DNA helicase II

• DNA helicase III

• DNA helicase IV

In mismatch repair mechanism, which of the following protein recognize DNA mismatches in the genomic DNA?

• MutH

• MutS

• MutL

• UvrD

The main difference between nucleotide excision repair (NER) and base excision repair (BER) is:

• In NER double strand breaks repaired where as in BER single strand breaks repaired

• NER is a light dependent reaction whereas BER is light independent process

• In NER phosphodiester backbone first cleaved where as in BER phosphodiester backbone is cleaved later

• All of these

Which enzyme is responsible for photoreactivation of DNA:

• Photoligase

• Photoreductase

• Photo-oxidase

• Photolyase

Which of the following enzyme(s) is involved base excision repair?

• DNA glycosylase

• AP endonuclease

• AP exonuclease

• (a), (b) and (c)

• Both (a) and (b)

Xeroderma pigmentosum in human associated with a mutation in

• Photoreactivation

• Nucleotide excision repair

• Base excision repair

• Mismatch repair

Which of the following statement is true regarding the nucleotide excision repair (NER) mechanism?

• NER mechanism is present only in eukaryotes

• NER present only in prokaryotes

• NER Present in both prokaryotes and eukaryotes but the exact mechanisms varies

• NER Present in both prokaryotes and eukaryotes with similar molecular mechanism in both

The catalytic activity of photolyase enzyme in the bacterial cells is activated by _________.

In NER (nucleotide excision repair) mechanism, the incision at the 3' position of the lesion is done by_________.