Biopharm Violet 1-100

1. It is the ability of a drug to exist in two or more crystalline form:

• A. Chirality
• B. Polymorphism
• C. Stereoisomerism
• D. A and C
• E. None of these

2. Arrange the following dosage forms from highest to lowest dissolution rate: I. Solution II. Capsule III. Suspension IV. Tablet

• A. I, II, III, IV
• B. I, III, II, IV
• C. IV, III, II, I
• D. IV, II, III, I
• E. None of these

3. All of the following statements aretrye regarding particle size of a drug, EXCEPT:

• A. Reducing the particle size can decrease the surface are the molecule exposed to the solvent.
• B. Reduction of paticle size can be achieved by micronisation using jet mill, spray drying and air attrition methods.
• C. The dissolution of some drugs available in the market has been improved by reducing the particle size.
• D. Reducing the particle size of a drug may increase drug absorption.
• E. None of these

4. Which of the following may increase drug dissolution rate? I. Too much binder II. Insoluble diluents III. High amount of lubricants

• A. I only
• B. I and II
• C. II and III
• D. I, II, AND III
• E. None of these

5. Which of the following is not true regarding the purpose of tablet coating?

• A. Improves palatability
• B. Improve aesthetic value of tablet
• C. Improve stability
• D. Improve in-vivo degradation
• E. None of these

6. A surface active agent that facilitates the absorption of lipophilic drug or water insoluble drugs

• A. Bile
• B. Albumin
• C. Renin
• D. Gastric acid
• E. None of these

7. Phase 2 metabolism that protects the body against chemically reactive metabolites

• A. Sulfate conjugation
• B. Glutathione conjugation
• C. Methylation
• D. Acetylation
• E. Glycine conjugation

8. All of the following listed below are processes of drug excretion, EXCEPT:

• A. Glomerular filtration
• B. Active secretion
• C. Tubular secretion
• D. Tubular reabsorption
• E. None of these

9. It is the basic functional unit of the kidney

• A. Glomerulus
• B. Loop of henle
• C. Nephron
• D. Collecting tubule
• E. None of these

10. Creatinine clearance of a patient with kidney failure

• A. 60-89 mL
• B. 30-59 mL
• C. 15-29 mL
• D. <15 mL
• E. None of these