Adult Stem Cells

What is your full name and school?

Name two areas in the body where adult stem cells can be found.

Adult stem cells and IPSCs (as well as ALL stem cells) go through _____________cell division. They have the ability to differentiate and self-renew.

Adult stem cells are pluripotent, similar to ESCs.

• True

• False. Adult stem cells are totipotent

• False. Adult stem cells are pluripotent while ESCs are multipotent

• False

Adult stem cells are considered to have limited potency potential because...

• They are partially differentiated and lineage committed.

• They are not quite as educated as ESC and IPSCs.

• They are not potent enough.

• They cannot different into specific cell types that are terminally differentiated.

Name one 'pro' of using adult stem cells in cell-based therapy

In the first ever stem cell transplant to a replace a collapse trachea, __________stem cells were used.

• Embryonic stem cells

• IPSCs

• Totipotent stem cells

• Pluripotent stem cells

• Adult stem cells

Name one origin from which adult stem cells can be extracted and used in an approved therapy (specifically discussed in lecture). Two word response only.

As with all stem cell therapy approaches, there are both advantages and disadvantages in using adult stem cells to treat diseases. Name one downside to using adult stem cells in therapy (one word response only).

The image above is a differentiation pathway of a neural stem cell (adult stem cell). Which of the following 'target' cell(s) was derived from the glial progenitor? Note: a target cell is a terminally differentiated cell aka a somatic cell.

• neuron

• astrocyte

• oligodendrocyte

• neuronal progenitor