Cancer 2

Which is not a hallmark of Cancer?

• Resisting cell death
• Inducing angiogenesis
• Inhibiting growth promoters
• Enabling immortality

Resisting Cell Death hallmark is best described when ...

• When the cell blocks apoptosis
• When the cell evades the signal
• When cells grow rapidly
• When cells evade suppressor proteins

During the cell cycle, the resting phase is ...

• G0
• G1
• G2
• S

Which of the following is not a way mutations occur in cellular DNA?

• UV radiation
• Genetics
• DNA repair proteins not working correctly
• Extreme cold

Tags

NGSS.HS-LS3-2

Sometimes cells have mutations that affect their function negatively. Most of the time, these cells will perform _________. However, cancer cells fail to do this and will continue to live and replicate.

• lytic annihilation
• platelization
• apoptosis
• synthesis

________________is a critical point where stop and go signals can regulate the cycle

• Metastasis

• Checkpoint

• Malignant

• Benign

Which of the following are checkpoints that the cell must pass before dividing?

• Have enough nutrients

• Be large enough to divide

• Have correctly copied all DNA

• All of the above

Tags

NGSS.HS-LS1-4

What is the role of protein kinases?

• remove phosphate groups to deactivate enzymes

• trigger apoptosis

• add phosphate groups and energy to activate enzymes

• stop the cell cycle

Which of these may be assessed by various proteins during a "checkpoint"? CHECK ALL THAT APPLY

• Ensure that all chromosomes have lined up in the center of the cell before sister chromatids separate

• Ensure that spindle fibers have attached to all centromeres before cell division

• Ensure that DNA has been replicated properly

Tags

NGSS.HS-LS1-4

Which description is true about cell cycle regulation?

• Changing concentrations of Cdk result in binding to cyclin
• Changing concentrations of cyclin result in binding to Cdk
• MPF complex formation decreases with increased Cdk levels
• MPF complex formation decreases with increased cyclin levels