Cancer and The Cell Cycle

What is the cell cycle?

• The gradual development of something, especially from a simple to a more complex form.
• The study of heredity and the variation of inherited characteristics.
• The branch of biology that deals with the relations of organisms to one another and to their physical surroundings.
• The series of events that take place in a cell leading to its division and duplication of its DNA to produce two daughter cells.

Which part of the Cell Cycle takes the longest?

• Interphase
• Mitosis
• Prophase
• Cytokinesis

Cells of organisms must go through cell division for?

• growth

• repair of damaged cells

• replacement of dying cells.

• All of these

Which of the following shows the correct sequence of the cell cycle?

• Mitosis-> G1->S->G2->cytokinesis
• S->G1-> G2-> mitosis-> cytokinesis
• cytokinesis->mitosis->G1->S->G2
•  G1->S->G2->mitosis->cytokinesis

There are different regulatory proteins that respond to events inside and outside the cell and these proteins affect cell growth.

• True

• False

Which of the following occur during cell Apoptosis? (select all that apply)

• cell membrane breaks

• cell growth

• DNA replication

• cell self-destructs / dies

Which of the following apply to cancer cells?

• performs mitosis normally

• lost control of the cell cycle

• lost control of mitosis

• all growth checkpoints work

• grow + divide uncontrollably

What is the main factor that causes a cell to become cancerous?

• changing the order of the cell cycle

• making to many proteins

• changes or defects to DNA

• environmental factors

Which of these may be assessed by various proteins during a "checkpoint"? CHECK ALL THAT APPLY

• Ensure that all chromosomes have lined up in the center of the cell before sister chromatids separate

• Ensure that spindle fibers have attached to all centromeres before cell division

• Ensure that DNA has been replicated properly

Which phrase best describes a common characteristic of all cancers?

• absence of cyclins
• damaged DNA
• uncontrolled cell growth
• inherited from parents