Complementary system

Which of the following pathway is involved in the adaptive immune response?

• a) Alternative Pathway

• b) Classical Pathway

• c) Lectin Binding Pathway

• d) All of the above

2. Which of the following isotype antibody is a potent activator of the classical complement pathway

• a) IgM

• b) IgA

• c) IgE

• d) IgG

3. In the classical pathway, which of the following complement complex serve as C3 convertase

• a) C4aC2a

• b) C4bC2b

• c) C4bC2a

• d) C4aC2b

4. Which component is cleaved by C4bC2aC3b and initiates the formation of membrane attack complex?

• a) C5

• b) C6

• c) C7

• d) C8

5. Classical pathway of complement system is activated by

• a) antibody-antigen complexes

• b) antigen

• c) antigenic peptides

• d) antigens bound to MHC

6. MAC is

• a) C5b6789 complex

• b) C5b5678 complex

• c) C5b5789 complex

• d) Protein polysaccharide complex

7. Classical pathway of complement system is involved in

• a) specific defence

• b) adaptive immunity

• c) both a and b

• d) non-specific defence

8. Complement component C3 is cleaved by

• A. C3b

• B. C3bBb

• C. Factor B

• D. Factor D

• E. Factor H  

9. which can be considered the key molecule in complement pathways?

• A) C1

• B) IgM

• C) MBL

• D) C5 convertase

10. Which of the following is considered anaphylatoxins produced during the complement cascade?

• A. C3a

• B. C3b

• C. C5a

• D. C5b

• E. Both C3a and C5a