Immunology Week 5

Which antibody class would be the worst at activating complement or immune cells?

• IgM

• IgG

• IgA

• IgE

Which of the following areas on an antibody would be responsible for causing an M1 macrophage to do phagocytosis?

• Variable region-light chain

• Variable region-heavy chain

• Hinge region

• Constant region

Which of the following is rearranged last during B-cell development?

• V-J, Heavy chain

• D-J, Heavy chain

• V-DJ, Light chain

• V-J, light chain

You have a mutation which does not allow T-cells to activate B-cells. Which of the following could still occur?

• Somatic Hypermutation

• Class Switching to IgG

• Formation of Plasma Cells

• Formation of Germinal Center

During T-cell dependent activation, which of the following is the LAST signal the B-cell receives before proliferation?

• Cytokines signaling by T-Cell

• MHC/BCR binding of same antigen

• Binding of free floating antigen

• Binding of antigen on APC

How does the B-cell enter a lymph node from the blood vessel?

• Low epithelial venule

• high epithelial venule

• loose epithelial venule

• hard epithelial venule

True or False: If your body would encounter an an antigen with an epitope it didn't have an BCR/B-Cell match for, it does VDJ recombination instantly to make one.

• True

• False

Which is last during T-cell development?

• Positive Selection

• Negative Selection

• Migration to the thymus

• Recombination/ Expression of TCR

MHC I binds to which cell?

• CD8 T cells

• CD4 T cells

• B Cells

• APC