Molecules 070323

Which of the following is correct about Carbon Monoxide?

• CO and O2 bind to Hb in equal status

• CO binds less readily to Hb than O2

• CO binds more readily to Hb than O2

• CO does not bind to Hb

The oxygen affinity of Hb is decreased (i.e. the oxygen dissociation curve is shifted to the right) when associated with

• Low CO2

  High 2, 3 - BPG

• High CO2

  Low 2, 3 - BPG

• Low CO2

  Low 2, 3 - BPG

• High CO2

  High 2, 3 - BPG

Myoglobin has _____ affinity for Oxygen compared with Haemoglobin.

• a higher

• a lower

• the same

The Bohr effect describes haemoglobin’s lower affinity for ____ secondary to increases in the partial pressure of carbon dioxide and/or decreased blood pH. This lower affinity, in turn, _____ the unloading of oxygen into tissues.

• CO

  enhances

• O2

  inhibits

• CO

  inhibits

• O2

  enhances

Regarding people who have acclimatized at Mount Everest base camp, which one of the following is correct?

• High myoglobin level

• The O2 dissociation curve will shift to the left

• Increased oxygen affinity

• The O2 binding to myoglobin graph will show a sigmoidal curve