Organic synthesis map #1

8. Haloalkane to alcohol

• NaOH/H₂O and reflux

• SOCl₂

• Reduced with LiAlH₄

• NaCN/Ethanol

11. Ketone to alcohol

• NaOH/H₂O and reflux

• SOCl₂

• Reduced with LiAlH₄

• NaCN/Ethanol

22. Acyl Chloride to Carboxylic acid

• NaOH/H₂O and reflux

• SOCl₂

• Reduced with LiAlH₄

• NaCN/Ethanol

Tags

NGSS.HS-PS1-4

NGSS.HS-PS3-1

6. Haloalkane to Nitrile

• NaOH/H₂O and reflux

• SOCl₂

• Reduced with LiAlH₄

• NaCN/Ethanol

Tags

NGSS.HS-PS1-5

23. Acyl chloride to Ester

• Acidified potassium dichromate, reflux

• H₂ and Ni

• Alcohol + Conc Acid

• NH₃

Tags

NGSS.HS-PS1-4

24. Acyl chloride to Amide

• Acidified potassium dichromate, reflux

• H₂ and Ni

• Alcohol + Conc Acid

• NH₃

Tags

NGSS.HS-PS1-4

7. Nitrile to Amine

• Acidified potassium dichromate, reflux

• H₂ and Ni

• Alcohol + Conc Acid

• NH₃

Tags

NGSS.HS-PS1-5

NGSS.HS-PS1-6

12 and 16. Alcohol to Carboxylic acid

• Acidified potassium dichromate, reflux

• H₂ and Ni

• Alcohol + Conc Acid

• NH₃

Tags

NGSS.HS-PS1-4

14. Ketone to hydroxynitrile

• X₂/ UV

• HX, room temperature

• H₂O

• NaCN/ H⁺

  Nucleophilic addition

21. Carboxylic acid to Acyl chloride

• X₂/ UV

• HX, room temperature

• H₂O

• NaCN/ H⁺

  Nucleophilic addition

Tags

NGSS.HS-PS1-4

NGSS.HS-PS1-2