ANTIMALARIAL DRUGS AND ANTHELMINTICS

Chloroquine is given as 600 mg loading dose because:

• (a) It is rapidly absorbed

• (b) It is rapidly metabolized

• (c) It has increased tissue binding

• (d) It is rapidly eliminated

The radical cure for P. vivax infection involves the administration of................................. 

A traveler to an Indian state where chloroquine-resistant P.falciparum is endemic develops a severe attack of P.falciparum malaria resistant to chloroquine. His treatment will include: 

      

• Quinine + Doxycycline

• Artesunate + Sulfadoxine-Pyrimethamine

• Mefloquine

• •Malarone

The serious adverse effect seen with mefloquine is:

• Nephrotoxicity

• Neuropsychiatric toxicities

• Severe arthritis

• Gynecomastia

Which of the following statements is TRUE about artemisinin derivatives?

     

• All have long t ½

• They are preferred for oral monotherapy

• Artemether is always given in combination with Sulfadoxine- Pyrimethamine

• They are never used for chemoprophylaxis

The drug of choice for treatment of filariasis is:

Which of the following antihelminthic drug is used for the treatment of Echinococcosis (Hydatid disease)?

• Pyrantel palmoate

• Thiabendazole

• Ivermectin

• Albendazole

Mazotti – like reaction is seen due to action of antihelmintic drugs on the microfilariae of:

             

• Enterobius vermicularis

• Onchocerca volvulus

• Ascaris lumbricoides

• Trichuris trichiura

Ivermectin is used for the treatment of:................................

Mebendazole cannot be used for:

• (a) Ascariasis

• (b) Entrobius vermicularis

• (c) Onchocercosis

• (d) Hydatid cyst disease