Mutations (H)

Which of the following mutations would be MOST likely to have a harmful effect on an organism?

• a deletion of three nucleotides near the middle of a gene.
• a single nucleotide deletion in the middle of an intron.
• a single nucleotide deletion near the end of a coding sequence.
• a single nucleotide insertion downstream of, and close to, the start of the coding sequence.

Tags

NGSS.HS-LS3-2

This type of substitution codes for a stop codon

• Missense
• Nonsense
• Silent
• Deletion

DNA molecule segment is : TTACGCAAG
The mutated DNA segment is TTCGCAAG. This is an example of ___ mutation.

• Substitution
• Deletion
• Insertion
• Inversion

Tags

NGSS.HS-LS3-2

Normal-
GAG-CTC-GAC-AGA
Mutant
GAG CTC-CAC-AGA

• no mutation
• substitution
• insertion
• deletion

Tags

NGSS.HS-LS3-2

If a point mutation does not change the order of the amino acid sequence, this is called a:

• nonsense mutation

• silent mutation

• missense mutation

• frameshift mutation

Tags

NGSS.HS-LS3-2

Insertions and deletions are also known as:

• frameshift mutations

• chromosomal mutations

• silent mutations

• polyploidy

Tags

NGSS.HS-LS3-2

If a mutation codes for "stop" in the amino acid chain, this is called a:

• nonsense mutation

• missense mutation

• silent mutation

• frameshift mutation

Tags

NGSS.HS-LS1-1

NGSS.HS-LS3-2

Match the following Mutations

• Causes an amino acid to change into a "STOP" codon

• Missense

• Has no effect on amino acids or proteins

• Silent

• Causes chance in amino acid sequence ; results in different protein

• Nonsense

Tags

NGSS.HS-LS3-2

What is the difference between the effect of a point mutation and a frameshift mutation?

Tags

NGSS.HS-LS3-2

Match the following mutations with their effect.

• deleted codon alters subsequent 3-code sequencesso different chain produced

• nonsense

  (substitution)

• extra codon alters subsequent 3-code sequences, so different chain produced

• silent

  (substitution)

• different codon is for same amino acid, so no effect

• missense

  (substitution)

• different codon causes early STOP, so polypeptide cut short

• insertion

  (frameshift)

• different codon changes amino acid, so some effect

• deletion

  (frameshift)

Tags

NGSS.HS-LS3-2