CT I Pharm 5109

Which one of the following is a mixed neurotranmitter (both excitatory and inhibitory)

• Glutamate

• Dopamine

• Histamine

• Serotonin

Insulin is an example of ---------- receptor

• Ionotropic

• Metabotropic

• Kinase-linked

• Nuclear receptors

End bulb of Krause is an example of-

• _{Mechanoreceptor}

• _Baroreceptor

• _{Chemoreceptor}

• _{Thermoreceptor}

What is the full form of AMPA receptors?

• Α - amino - 3 - hydro- 5 - methoxy - 4 - isoxozolepropionic acid

• Α - amino - 3 - hydroxy - 5 - methyl - 4 - isoxozolepropionic acid

• Α - amino - 3 - hydroxy - 5 - methyl - 4 - propionic acid

• Α - amino - 3 - methyl - 4 - propionic acid

Functional ionotropic glutamate receptors are ------------ assemblies between subunits from ------------ major subfamilies.

• Tetrameric, three

• Pentameric, four

• Trimeric, three

• Pentameric, three

Open-channel block, a form of --------------- antagonism

• competitive

• uncompetitive

• partial

• reverse

Memantine is not used to treat--------------

• Alzheimer's diseae

• Dementia

• Glaucoma

• Seizures

Which of the following statement is not true?

• Barbiturates are GABA agonists

• Neurosteroids are GABA antagonists

• Bicuculline is a GABA antagonist

• Picrotoxin is a GABA antagonist

GABA_a receptors are drawn from a pool of---------- distinct gene products

(a)  

Which of the following statement is not true about GABAb receptors?

• GABAb₁ and GABAb₂ both subunits are essential

• The location of the recognition site is on GABAb₁

• G_o or _i are the location of the G protein-binding site on GABAb₂

• Baclofen is a receptor recognition site antagonist