Pharm

Pharmacodynamics is

• what the drug does to the body

• what happens to the drug once it enters the body

• what happens to the drug once it leaves the body

Pharmacokinetics is

• what the drug does to the body

• what happens to the drug once it enters the body

• what the drug does once it leaves the body

Parameters of pharmacokinetics... select all that apply

• Absorption

• distribution

• metabolism

• excretion

administration site to the bloodstream

• distribution

• absorption

• metabolism

• excretion

bloodstream to the target organ receptors

• metabolism

• excretion

• distribution

• absorption

breaking down remaining drug for elimination

• excretion

• metabolism

• absorption

• distribution

drug eliminated from the body

• excretion

• distribution

• absorption

• metabolism

Passive diffusion is how drugs move through the body via

• high to low concentration

• carrier proteins

• active energy

A 3 week old neonate with pulmonary edema is getting lasix IV daily at 1 mg/kg/dose, he is now getting full feeds and switched to 2mg/kg PO. Why would his dose need increased?

• bioavailability

• volume distribution

• passive diffusion

when does first pass metabolism take place

• oral administration

• IM administration

• IV administration

• percutaneous medication administration