BIOCEL 02

_____________ are mitochondrial machineries for protein import and assembly

• TIM/TOM complex
• TIC/TOC complex
• TIC/TAC complex
• TIM/TOC complex
• TIC/TOM complex

This complex consists of receptor components for the initial contact with preproteins at the mitochondrial surface and membrane-embedded proteins which promote transport and form the translocation pore.

• TOM
• TIM
• TIC/TAC complex
• TOC
• SAM

Is a dimeric protease in the mitochondrial matrix that removes N-terminal presequences

• Mitochondrial processing peptidase
• Translocase of the inner membrane 23
• Translocase of the inner membrane 22
• Mitochondrial processing peptidase
• Translocase of the outer mitochondrial membrane

The________________ are interacting proteins that help to prevent the precursor proteins from aggregating or folding up spontaneously before they engage with the TOM complex in the outer mitochondrial membrane

• small TIM chaperones
• presequence translocase-associated motor proteins
• cysteine-rich proteins
• β-barrel proteins
• translocation proteins

Defects in mitochondrial transport are a suspected cause of diseases including Alzheimer's, Huntington's and Parkinson's. ATP hydrolysis fuel mitochondrial protein directional transport at:

• the outer membrane and into the matrix space
• the intermembrane and into the matrix space
• the cristae and intermembrane
• the outer, inner and inter membrane
• the intermembrane and inner membrane

It is a protein complex export translocase in the mitochondrial inner membrane (homologous to prokaryotic YidC)

• Oxidase assembly complex
• Translocase of the inner membrane 23
• Translocase of the inner membrane 22
• Mitochondrial heat-shock protein complex
• Presequence translocase-associated motor proteins

Binds to the C-terminal cytosolic target signal receptor protein (SKL-type) that accompanies vesicle all the way into peroxisomes and, after its release, cycles back to the cytosol

• cytosolic receptor Pex5p
• cytosolic receptor Pex6p.
• cytosolic receptor Pex1p
• cytosolic receptor Pex15p
• cytosolic receptor Pex7p

Binds to the N-terminal cytosolic target signal receptor protein (SKL-type) that accompanies vesicle all the way into peroxisomes and, after its release, cycles back to the cytosol

• cytosolic receptor Pex7p
• cytosolic receptor Pex5p
• cytosolic receptor Pex6p
• cytosolic receptor Pex1p
• cytosolic receptor Pex15p

The pathway that is dominantly used to translocate secretory and membrane proteins is known as:

• co-translational transport
• post-translational transport
• pre-translational transport
• gated transport
• vesicular transport

The membrane of the ER harbors a protein translocon with 3 different subunits (heterotrimeric), which facilitates membrane integration or translocation of almost every newly synthesized polypeptide targeted to organelles of the endo and exocytotic pathway called:

• All answers are correct
• Sec61 complex
• Sec61β
• Sec61α1 and Sec61α2
• Sec61γ