DevBio Fetal Alcohol Syndrome

Ethanol causes an increase in intracellular ________.

• B-catenin

• Shh

• Calcium

• Sodium

Choose the correct statement.

• Inhibiting CaMKII increases NCC apoptosis.

• Inhibiting CaMKII does not affect NCC apoptosis.

• Inhibiting CaMKII decreases NCC apoptosis.

Ethanol is the leading human teratogen.

• True

• False

The central effector of ethanol's neurotoxicity is:

• Calcium

• Frizzled

• Wnt

• B-catenin

Pre-natal alcohol exposure effects how many live births in the U.S.?

• 0-100/1000

• 100-200/1000

• 200-300/1000

• All of them

FAS is the leading cause of preventable intellectual disability.

• True

• False

With forced expression of B-catenin in ethanol-treated emrbyos, the amount of apoptotic cells ________.

• Increased

• Decreased

• Did not change

With forced expression of dominant-negative TCF, which represses B-catenin/TCF activity, the amount of NCC apoptosis _________.

• Increased

• Decreased

• Did not change

Which of the following are characteristic of FAS?

• Upturned nose

• Underdeveloped jaw

• Flat philtrum

• All of these