BIOCEL 04

Gold nanoparticles below a certain size limit that are injected into the cytoplasm can later be observed in the nucleus. This is explained by which of the following:

• Molecules below a certain size can diffuse nonselectively through the nuclear pore complex.
• There are gold-specific ion channels on the nuclear envelope.
• Gold particles contain a nuclear localization signal.
• The DNA requires gold to function effectively.
• Gold is recognized as valuable and is escorted into the nucleus by a nuclear transport receptor.

The carbohydrate groups found on the extracellular surface of the plasma membranes were 'installed' by cellular machinery__________.

• on the luminal side of the ER and Golgi membranes.
• in the cytosol.
• on the cytosolic side of the ER and Golgi membranes.
• on the luminal side of the ER membrane and the cytosolic side of the Golgi membrane.
• on the cytosolic side of the ER membrane and the luminal side of the Golgi membrane.

A transmembrane protein destined for the plasma membrane protrudes from the cytosolic face of the ER membrane. On its journey to its destination, where would you expect the protein to protrude?

• on the cytosolic face of the Golgi, and on the cytosolic face of the plasma membrane
• on the non-cytosolic face of the Golgi, and on the extracellular face of the plasma membrane
• on the non-cytosolic face of the Golgi, and on the cytosolic face of the plasma membrane
• on the cytosolic face of the Golgi, and on the extracellular face of the plasma membrane
• I have absolutely no idea.

HsDynamin-1

• is involved in Clathrin-mediated endocytosis.
• is responsible for cleaving the stretch amino acid sequence 'sorting signals' from N-terminals of proteins once the sorting process is completed in eukaryotic cells.
• I have absolutely no idea.
• depicts a paradigmatic endogenous theory scenario
• is envolved in re-targeting or relocalization of proteins to different compartments

Stages in vesicle delivery:

• Tethering-Docking-Fusion
• Docking-Tethering-Fusion
• Docking-Fusion-Tethering
• Fusion-Docking-Tethering
• Tethering-Fusion-Docking

Key proteins in vesicular movement are:

• All answers are correct
• Rab
• Snare
• tSNARE
• vSNARE

An adapter protein__________.

• All answers are correct
• is on the coat of a vesicle
• binds to sorting signal in the transmembrane protein
• couples transmembrane protein with protein coat of budding transport vesicle
• is regulated by ARF and Rab

COP I and COP II:

• COP I coated vesicles travel from the Golgi to the ER and COP II coated vesicles travel from the ER to the Golgi.
• COP I coated vesicles travel from the ER to the Golgi and COP II coated vesicles travel from the Golgi to the ER.
• are two clathrin proteins that coat transport vesicles
• are regulated by ARF and Rab
• None of the answers are correct

membrane protein that acts with some other membrane protein that has to be binded for HIV to enter. CXCR4 and CCR5

• Co-Receptor
• Receptor
• vSNARE
• tSNARE
• vSNARE is binded to vesicle, tSNARE is on membrane where Tethering occurs

In Vesicular transport, budding _________________.

• releases material out of the organelle
• releases material inside the nucleus
• releases material inside the Golgi
• releases material inside the ER
• I have absolutely no idea