Cancer Biology_Ch8_2023_3377

__________ is the process of programmed cell death.

• Apoptosis

• Necrosis

• Autophagy

• Senescence

_________is a morphological characteristic of apoptosis.

• Cell swelling and rupture

• Nuclear fragmentation and condensation

• Plasma membrane swelling

• Increased mitochondrial membrane potential

Which caspase (s) is (are) initiator caspase (s) in the extrinsic pathway of apoptosis?

• Caspase-6

• Caspase-6 and -7

• Caspase-8

• Caspase-3 and -9

_________is involved in the intrinsic pathway of apoptosis.

• Endoplasmic reticulum

• Mitochondria

• Nucleus

• Golgi apparatus

__________is a characteristic of necrosis?

• Energy-dependent process

• Controlled and regulated process

• Inflammatory response

• Cell shrinkage and condensation

__________ is the function of the apoptosome.

• To activate effector caspases

• To cleave DNA

• To release cytochrome c

• To induce plasma membrane blebbing