Ryzodeg QUIZ May 2023

In step by step trial primary end point was Change from baseline in HbA1c after 26 weeks.

• True

• False

Nocturnal confirmed hypoglycaemia with IDegAsp lower in step by step trial after 26 weeks was ____ and after 38 weeks was ____ ?

• 43%, 34%

• 45%, 39%

• 41%, 14%

• None of these

In step by step trial patients included treated with regimen like.

• OADs

• Basal Insulin

• Basal Bolus Insulin

• on Premix Insulins in previous 3 months

Initial Starting dose of Insulin Aspart in Step by Step intensification trial was

• 4 Units

• 6 Units

• 8 Units

• According to Body weight

Confirmed hypoglycaemia in step by step intensification trial ____ lower at week 26, ____ lower at week 38.

• 14%, 10%

• 12%, 14%

• 10%, 14%

• 15%,20%

Total number of patients included in step by step intensification trial.

• 521 patients

• 532 patients

• 582 patients

• 696 patients

CONFIRM trial is comparative effectiveness of degludec (either 100 or 200 units/mL) versus glargine U300 in insulin-naïve adult patients with T2D.

• True

• False

In CONFIRM trial Primary end point was _____ from the initiation date.

• Change in overall Hypos

• Change in mean HbA1c

• Change in FPG & PPG

• Change in Insulin Dose

In Confirm Trial Exploratory end point was the change in Mean basal insulin dose (units/day) at 90-day follow-up.

• True

• False

Total number of patients in both treatment arms after propensity score matching in CONFIRM Trial.

• 6375 pts

• 4056 pts

• 4413 pts

• 4202 pts