Mini Quiz 1: DNA Replication

1.      Replication of DNA is based on the

• Semi-conservative model

• Conservative model

• Dispersive model

• Template model

DNA replication occurs during ​ (a)   whereby one parental DNA molecule produces ​ (b)   .

• S Phase
• two daughter DNA molecules.
• M Phase
• Prophase
• Anaphase
• four daughter DNA molecules
• a new mRNA molecule

The following are enzymes involved in DNA replication EXCEPT

• Primase

• DNA polymerase III

• DNA Ligase

• DNA reductase

Reorder the following:

• Primase adds RNA primer which will be the 5’ end of the new strand

• Helicase unwinds DNA by breaking hydrogen bonds.

• DNA polymerase III binds to primer and synthesizes new DNA strand in 5’ to 3’ direction.

• DNA polymerase I replaces the primers with DNA nucleotide.

Which of the following statements are FALSE?

(Could be more than one)

• The lagging strand is synthesized in 3’ to 5’ direction

• DNA replication will produce a leading strand and lagging strand

• DNA replication terminates when all the DNA bases have been replicated

• SSB Protein relieves strain by breaking, swivelling, and rejoining DNA strands

• Okazaki fragments are joined together by DNA Lipase

What will happen if all DNA polymerase III enzymes in the cell are denatured?

• DNA replication cannot be completed

• RNA primer cannot be replaced with DNA nucleotides

• DNA double helix cannot be unwound

• New DNA strands cannot be synthesized