Circadian Clock and Gene Expression
Authored by Rachel Besing
Science
University
Used 2+ times
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11 questions
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1.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which transcription factor dimerizes with CLOCK in the mammalian circadian clock?
BMAL1
PER
CRY
Rev-erb
2.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What happens when PER and CRY proteins interact with the CLOCK/BMAL1 dimer?
They promote transcription of per and cry genes
They inhibit transcription of per and cry genes
They degrade CLOCK and BMAL1 proteins
They stop the production of new transcripts for PER and CRY
3.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which transcription factors control Bmal1 transcription?
ROR alpha, beta, and gamma
PER and CRY
Rev-erb alpha and beta
CLOCK and BMAL1
4.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What are the other genes that have clock-dependent expression called?
Transcription factors
Response elements
Clock-controlled genes
Enhancer boxes
5.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which gene is an example of a clock-controlled gene critical for cellular metabolism?
CLOCK
BMAL1
Nampt
Rev-erb
6.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What happens to NAMPT expression when the circadian clock is disrupted?
It increases
It becomes arrhythmic
It stops oscillating
It decreases
7.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
In which tissues has the decrease and arrhythmic expression of NAMPT been observed in circadian clock mutant models?
Liver
Brain
Muscle
All of the above
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