Protein Synthesis & Mutations

What is the order of the steps in protein synthesis?

• Translation, then Transcription

• Transcription, then Replication

• Transcription, then Translation

• Translation, then Replication

Put the steps of central dogma and protein synthesis in the correct order

• DNA

• Transcription

  -->

• RNA

• Translation

  -->

• Protein

Tags

NGSS.HS-LS1-1

NGSS.HS-LS1-6

During transcription, a sequence of ​ (a)   is copied onto a strand of ​ (b)   so that it can leave the ​ (c)   to find a ​ (d)   .

• DNA
• mRNA
• nucleus
• ribosome

During translation, the code from ​ (a)   is read by the ​ (b)   and translated into a sequence of ​ (c)   .

• mRNA
• ribosome
• amino acids

What is the job of tRNA?

• Carry amino acids to the ribosome during protein synthesis
• Facilitate cell division
• Store genetic information
• Transcribe DNA into RNA

Determine the correct order of the amino acid sequence to be produced from the DNA template:

3' CCG TCT AAG GTG ACC CTT 5'

• Valine - Threonine - Lysine - Serine - Proline - Glutamic Acid

• Glycine - Valine - Lysine - Serine - Proline - Alanine

• Proline - Serine - Lysine - Threonine - Valine - Stop

• Glycine - Arginine - Phenylalanine - Histidine - Tryptophan - Glutamic Acid

Tags

NGSS.HS-LS1-1

Determine the correct amino acid sequence from the mRNA strand:

5' AUG CAG UCU GCA CUG AGC 3'

• Met-His-Ser-Ala-Leu-Ser

• Met-Arg-Ser-Ala-Leu-Ser

• Met-His-Ser-Leu-Ala-Ser

• Met-Gln-Ser-Ala-Leu-Ser

Tags

NGSS.HS-LS1-6

Which amino acid is coded for by the following mRNA codon CCU?

Tags

NGSS.HS-LS1-6

Determine the correct amino acid sequence from the mRNA strand:

5' UAU GCC GUA CGC GAA CAC 3'

• Tyrosine - Glycine -Valine - Arginine -Glutamic Acid -Histidine

• Tyrosine - Alanine -Leucine - Arginine -Glutamic Acid -Histidine

• Tyrosine - Alanine -Valine - Arginine -Glutamic Acid -Histidine

• Tyrosine - Alanine -Valine - Arginine -Glutamic Acid - Asparagine

Tags

NGSS.HS-LS1-1

NGSS.HS-LS1-6

Match the type of mutation with its definition:

• Substitution

• when one nucleotide is switched for a different one in the DNA sequence

• Insertion

• when one nucleotide is removed from the DNA sequence

• Deletion

• when one nucleotide is added into the DNA sequence

Tags

NGSS.HS-LS3-2