Adaptive immune response review

Which of the following mechanisms generate a diverse TCR and BCR repertoire?

• VDJ recombination

• Somatic hypermutation

• Affinity maturation

• KFC rearrangement

Which CD4 T cell subset is most suitable for a response against extracellular bacteria and fungi?

• Th1

• Th2

• Th17

• Treg

Which CD4 T cell subset is most suitable for an anti-helminthic response?

• Th1

• Th2

• Th17

• Tfh

Which of the following T cell subsets helps suppress inflammation?

• Th1

• Th2

• Th17

• Treg

Which of the following cytokines help induce T cell survival and proliferation?

• IFNgamma

• IL-10

• IL-2

• IL-17

Activated B cells produce which kind of protein?

• Antibodies

• Anti-terrorism

• Plasma cells

• Perforin/granzyme

Which of the following antibody isotypes is best for anti-parasitic immunity?

• IgA

• IgM

• IgE

• IgD

Which antibody isotype is first produced during any immune response?

• IgA

• IgE

• IgG

• IgM

Which of the following increases the ability of antibodies to bind strongly to their antigens?

• Affinity maturation

• VDJ recombination

• Class switch recombination

Where do T cells mature?

• • A) Bone marrow

• • B) Thymus

• • C) Spleen

• • D) Liver