PHG402 Quiz Lecture 7

Cephalosporium acremonium produces Cephalosporin C which is

• penicillinase-resistant and active against Gram-positive bacteria.

• penicillinase-resistant

• penicillinase-resistant and active against Gram-negative bacteria

• penicillinase-sensitive and active against Gram-negative bacteria

An antibiotic substance isolated from Pseudomonas pyrrocinia, with high antifungal activity against dermatophytic fungi.

• Cephalosporin P1

• Pyrrolnitrin

• salinosporamide A

• Cyclomarine A

A unique beta-lactone which is in Phase III clinical trials for glioblastoma brain cancer

• Cephalosporin P1

• Pyrrolnitrin

• salinosporamide A

• Cyclomarine A

A The cyclic peptide that has has potent antimalarial and anti-Mycobacterium tuberculosis activity

• Cephalosporin P1

• Pyrrolnitrin

• salinosporamide A

• Cyclomarine A

................................ showed P-gp inhibition activity

• Didemnin B

• thalassospiramides

• Chrysosporazines

• Anthracimycin