Neurodegenerative Diseases Quiz

Although a highly debated topic in the literature (due to some messy science), what is the primary biomarker for Alzheimer's disease?

• Tau proteins

• Amyloid-beta plaques

• Dopamine

• Serotonin

Which of the following is NOT a symptom of Alzheimer's disease in its early stage?

• Memory problems

• Difficulty concentrating

• Hallucinations

• 1. Disorientation in time or location

Which gene mutation is associated with early-onset Alzheimer's disease?

• APP

• PSEN1

• PSEN2

• All of the above

What is the primary cause of Parkinson's disease?

• Loss of dopamine-producing cells in the substantia nigra

• Overproduction of serotonin in the brain

• Formation of beta-amyloid plaques in the brain

• Mutation in the APP gene

Which of the following is NOT a symptom of Parkinson's disease?

• Slow movement

• Muscular rigidity

• Poor coordination

• Memory loss

Which of the following treatments is used for Parkinson's patients who do not respond adequately to medication?

• Deep brain stimulation (DBS)

• Levodopa (L-Dopa)

• Cholinesterase inhibitors

• Beta-amyloid antibodies

What is the primary cause of Amyotrophic Lateral Sclerosis (ALS)?

• Loss of dopamine-producing cells in the substantia nigra

• Death of motor neurons leading to the degeneration of communication between the brain and spinal cord

• Formation of beta-amyloid plaques in the brain

• Mutation in the APP gene

Which of the following is NOT a symptom of Huntington's disease?

• Irritability

• Small involuntary movements

• Difficulty making decisions

• Hallucinations

What causes Huntington's disease?

• Mutations in the HTT gene on chromosome 4

• Loss of dopamine-producing cells in the substantia nigra

• Formation of beta-amyloid plaques in the brain

• Mutation in the APP gene

Which was the most challenging disease to understand through this lecture?

• Alzheimer's disease (AD)

• Parkinson's disease

• Amyotrophic Lateral Sclerosis (ALS)

• Huntington's disease