CAMs and Cell Adhesion

What are cell-adhesion molecules (CAMs) and what is their role in cell adhesion?

• Lipids responsible for energy storage

• Carbohydrates involved in DNA replication

• Proteins involved in photosynthesis

• Proteins involved in binding with other cells or with the extracellular matrix, mediating cell-cell adhesion and cell-matrix adhesion.

Name and describe the three major types of cell junctions.

• Smooth junctions, rough junctions, and sticky junctions

• Loose junctions, open junctions, and weak junctions

• Round junctions, square junctions, and triangular junctions

• Tight junctions, gap junctions, and desmosomes

How do cadherins contribute to cell-cell adhesion?

• Cadherins break the adhesion between cells

• Cadherins only adhere to extracellular matrix, not to other cells

• Cadherins mediate cell-cell adhesion by binding to other cadherins on adjacent cells.

• Cadherins have no role in cell-cell adhesion

Explain the role of integrins in cell adhesion and signaling.

• Integrins mediate cell adhesion to the extracellular matrix and to each other, and also play a role in cell signaling.

• Integrins only mediate cell adhesion to other cells, not to the extracellular matrix

• Integrins are not involved in cell adhesion or signaling

• Integrins play a role in cell adhesion but not in cell signaling

What are the functions of tight junctions in cell adhesion?

• Allow the leakage of molecules between cells

• Seal the intercellular space and prevent the leakage of molecules between cells

• Act as energy storage for the cell

• Regulate the cell's response to external stimuli

Describe the structure and function of desmosomes in cell adhesion.

• Desmosomes are found in plant cells

• Desmosomes are specialized cell junctions that provide strong adhesion between cells.

• Desmosomes are responsible for transporting nutrients between cells

• Desmosomes are involved in cell division

What are the differences between adherens junctions and focal adhesions?

• Adherens junctions and focal adhesions are the same thing

• Adherens junctions and focal adhesions are both found in plant cells

• Adherens junctions are involved in cell-matrix adhesion, while focal adhesions are involved in cell-cell adhesion

• Adherens junctions are cell-cell adhesions, while focal adhesions are cell-matrix adhesions.

Explain the significance of cell adhesion in tissue development and maintenance.

• Tissue development and maintenance can occur without cell adhesion

• Cell adhesion only affects individual cells and not tissue formation

• Cell adhesion has no significance in tissue development and maintenance

• Cell adhesion is crucial for tissue development and maintenance as it allows cells to stick together and form tissues, organs, and organ systems. It also plays a role in cell signaling, migration, and differentiation.

How do selectins contribute to cell adhesion and migration?

• Selectins inhibit the attachment of leukocytes to the endothelium

• Selectins only mediate attachment of red blood cells to the endothelium

• Selectins mediate the initial attachment of leukocytes to the endothelium during inflammation.

• Selectins are not involved in cell adhesion and migration

Discuss the role of cell adhesion in cancer metastasis.

• Cell adhesion has no impact on cancer metastasis

• Cell adhesion only affects healthy cells

• Cell adhesion facilitates the spread of cancer cells to other parts of the body.

• Cell adhesion prevents the spread of cancer cells