pk exam 2: Drug Elim & Hepatic CL part 1 stopped at 1-27
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48 questions
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1.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Drugs eliminated unchanged through the kidney.
renal clearance
hepatic clearance
2.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
drugs eliminated by metabolism in the liver
renal clearance
hepatic clearance
3.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Renal clearance and hepatic clearance are ____ on/of each other
dependent
independent
Answer explanation
and they are additive
4.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Drugs that are eliminated by _____ display large inter-individual variability due to genetic and environmental factors.
renal clearance
hepatic metabolism
5.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Drugs that are eliminated by _____ are highly dependent on the glomerular filtration rate and blood flow to the kidney
renal clearance
hepatic metabolism
6.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which displays LESS ineter-individual variability?
renal clearance
hepatic metabolism
Answer explanation
GFR is relatively constant among healthy individuals. There is a "normal" measurement for GFR.
7.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
If renal excretion pathway becomes impaired What will become the primary drug elimination route?
renal clearance
hepatic metabolism
Answer explanation
more heavily reliant on the liver.
the opposite is true if the liver is damaged.
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