CHAPTER 4 HEMATOPOIESES

1. The normal sequence of blood cell development is

• A. yolk sac—red bone marrow—liver and spleen
• B. yolk sac—thymus—liver and spleen—red bone marrow
• D. liver and spleen—yolk sac—red bone marrow
• C. yolk sac—liver and spleen—red bone marrow

2. The maturational sequence of the thrombocyte (platelet) is

• A. megakaryoblast— promegakaryocyte—megakaryocyte—metamegakaryocyte—thrombocyte
• B. promegakaryocyte—megakaryocyte—metamegakaryocyte—thrombocyte
• C. megakaryoblast—promegakaryocyte--megakaryocyte—thrombocyte
• D. megakaryoblast—promegakaryocyte—metamegakaryocyte—thrombocyte

3. The maturational sequence(s) of the erythrocyte is (are)

• A. rubriblast—prorubricyte—rubricyte—metarubricyte—reticulocyte—mature erythrocyte
• B. prorubricyte—rubricyte—metarubricyte—reticulocyte—mature erythrocyte
• C. pronormoblast—basophilic normoblast—polychromatophilic normoblast—orthochromic--normoblast—reticulocyte—mature erythrocyte
• D. both A and C

4. The cell maturation sequence of the segmented neutrophil is

• A. promyelocyte—myeloblast—myelocyte—metamyelocyte—band or stab—segmented neutrophil(PMN)
• B. myeloblast—promyelocyte—myelocyte—metamyelocyte—band or stab—segmented neutrophil(PMN)
• C. monoblast—promyelocyte—myelocyte—metamyelocyte—band or stab—segmented neutrophil(PMN)
• D. promyelocyte—myelocyte—metamyelocyte—band or stab—segmented neutrophil (PMN)

5. As a blood cell matures, the overall cell diameter in most cases

• A. increases
• B. decreases
• C. remains the same

6. As a blood cell matures, the ratio of nucleus to cytoplasm (N:C) in most cases

• A. increases
• B. decreases
• C. remains the same

7. The chromatin pattern, in most cells, as the cell matures

• A. becomes more clumped
• B. becomes less clumped
• C. remains the same

8. The presence of nucleoli is associated with

• A. immature cells
• B. all young cells, except myeloblasts
• C. only erythroblasts
• D. disintegrating cells

9. In the blast stage of development of leukocytes, the cytoplasm of the cell is

• A. dark blue and lacks vacuoles
• B. light blue and lacks granules
• C. light blue and has specific granules
• D. gray with many dark-blue granules

Segmented neutrophil

• A. Large orange granules
• B. An elongated and curved nucleus
• C. Light, sky-blue cytoplasm
• D. Kidney bean–shaped nucleus
• E. Averages approximately 56% of normal adult leukocytes in the peripheral blood