Module 4 Antigen Recognition in the Adaptive Immune System

Which of the following is found in the Fc region of antibodies?

• Heavy chains only

• Light chains only

• Heavy and light chains

• None of the above

The Fab region of an antibody molecule contains:

• Variable heavy and variable light chains

• Constant light and constant heavy chains

• Complementarity Determining Regions

• All of the above

2. What do you call the parts of antigens that are recognized by antibodies?

• CDR

• Antibody-binding complex

• Epitopes

• Fab

Region of antibody responsible for its flexibility?

• Fab

• Fc

• Hinge

• Tail

Aside from the heavy chain locus, where else can you find the D gene segment involved in somatic recombination?

• Kappa light chain

• Lambda light chain

• TCR alpha chain

• TCR beta chain

What is responsible for the diversity in the lambda chain of antibodies?

• VDJ recombination

• VJ recombination

• Both

• None of the above

Repeated antibody exposure resulted to change in Kd from 10^-7 to 10^-10.

• Isotype switching

• Affinity maturation

• Cross reactivity

• Avidity maturation

Which antibody forms a pentamer around a J chain?

• IgE

• IgM

• IgG

• IgD

• IgA

What is the most abundant Ig isotype in the blood?

• IgG

• IgD

• IgE

• IgM

• IgA

The is antibody found in the tears?

• IgA

• IgE

• IgG

• IgM

• IgD