Paracetamol

The minimum blood volume for adult TDM sample is 1 ml.

• True

• False

The blood sample for TDM paracetamol should be collected in a plain tube.

• True

• False

If the blood sample for TDM paracetamol is accidentally filled into an EDTA tube, it can still be removed out and filled into the plain tube.

• True

• False

The toxic paracetamol dose for adult is 5 to 7.5 g.

• True

• False

Patient took 10 paracetamol tablets at 6 am. The earliest time to sample for PCM will be at 10 am.

• True

• False

Patient took T. PCM XR 650 mg x 10 tablets at 12 pm. First TDM is taken at 6 pm upon admission to ETD. The next sample should be taken at 9 pm.

• True

• False

Rumack-Matthew nomogram can be extrapolated to a maximum of 36 hours.

• True

• False

For patient presented >24 hours after acute PCM ingestion, consider toxic if level ≥ 10 mg/L.

• True

• False

Oral NAC can be given as an alternative if patients experienced allergic reaction due to IV NAC.

• True

• False