180 Week 6: Cardio Meds

What is the mechanism of action (MOA) of Statins (HMG-CoA Reductase Inhibitors)?

• Increase the production of cholesterol

• Interfere with the synthesis of cholesterol

• Reduce the excretion of sodium and water

• Vasodilation of the small arteries

Which of the following are complications associated with Statins? (Select all that apply)

• Hepatotoxicity

• Myopathy

• Hypotension

• Bleeding

• Edema

What should patients be instructed to do when taking Statins?

• Take the medication with grapefruit juice

• Monitor CK levels periodically throughout treatment

• Only take the medication for short-term periods

• Increase intake of fatty foods

Which are therapeutic uses of Angiotensin-Converting Enzyme (ACE) Inhibitors? [Select all that apply]

• Hypertension

• Heart failure

• Myocardial infarction

• Atrial fibrillation

• Gout

Which is a contraindication/precaution for Statins? [Select all that apply]

• Pregnancy Category X

• High blood pressure

• Diabetes

• Smoking

• Liver disease

What is the MOA of ACE Inhibitors?

• Block the production of renin into angiotensin I

• Reduce the synthesis of cholesterol

• Reduce the production of angiotensin II by blocking angiotensin I

• Increase the excretion of potassium

Which medication is primarily associated with the side effect of rash and dysgeusia (altered taste)?

• Hydrochlorothiazide

• Captopril

• Enalapril

• Epinephrine

What is the recommended action if a patient develops a cough while on ACE inhibitor therapy?

• Increase the dose

• Take an antitussive

• Discontinue the medication

• Administer diphenhydramine

ACE inhibitors interact with which medications? [Select all that apply]

• Hydrochlorothiazide

• Lithium carbonate

• NSAIDs

• Alendronate

• Calcium carbonate

Enalapril is unique among ACE inhibitors because it can be administered in which way?

• Orally

• Intramuscularly

• Intravenously

• Subcutaneously