PG2042-Photochemistry and Natural Products

The structure of reserpine was elucidated from which plant?

• Rauwolfia serpentina     

• Atropa belladonna   

• Papaver somniferum

• Dictamnus albus

What are alkaloids primarily known for?

• Providing color to flowers      

• Acting as antioxidants

• Exhibiting pharmacological activity     

• Enhancing plant growth

Reserpine acts by

• Blocking alpha-adrenergic receptors     

• Inhibiting the reuptake of norepinephrine

• Depleting stores of monoamines in nerve terminals

• Directly stimulating the parasympathetic nervous system

Which of the following functional groups is NOT present in reserpine?

• Ester linkage

• Methoxy group      

• Amide linkage        

• Phosphate group

What is a synthon in retrosynthetic analysis?

• A protecting group used to shield reactive functional groups.

• A stable, readily available compound that can be used as a precursor in synthesis.

• An activating group that increases the reactivity of a functional group.

• A term used interchangeably with "retrosynthetic equivalent."

In the retrosynthetic analysis of a target molecule, a one functional group disconnection implies:

• The removal of a protecting group.

• Breaking a specific bond to create two fragments.

• The use of an activating group to enhance reactivity.

• Employing a convergent approach in synthesis.

Why are protecting groups used in organic synthesis?

• To enhance the reactivity of functional groups.

• To prevent unwanted reactions or side reactions.

• To increase the stability of the target molecule.

• To promote a convergent approach in retrosynthesis.

Which retrosynthetic terminology is associated with the disconnection of a specific functional group in the target molecule?

 

• Linear approach

• Convergent approach

• Functional group disconnection

• Protecting group strategy

Which starting materials would likely result from the retrosynthetic disconnection of a 1,3-dicarbonyl compound?

• Two alkyl halides

• An alkyl halide and a carboxylic acid

• A ketone and an aldehyde

• An ester and a carboxylic acid

In the retrosynthesis of 1,5-dicarbonyl compounds, a 1,5-disconnection is aimed at creating precursors that are:

• Two separate ketones.  

• A diester.   

• An aldehyde and a ketone.

• A ketone or aldehyde and a nitrile.