Lecture 4 Quiz

What determines the structure of a protein?

• Number of electrons
• Type of bond
• Temperature of the environment
• Amino acid sequence

What is myoglobin primarily responsible for?

• Storing oxygen in muscle cells
• Regulating blood sugar levels
• Producing bile in the liver
• Transporting nutrients in the bloodstream

During evolution, what aspect of proteins is most conserved?

• Length of the protein
• Function of the protein
• Structure of the protein
• Sequence of amino acids

Which family do myoglobin and hemoglobin both belong to?

• Hemoglobin
• Protein
• Enzyme
• Globin

How is protein structure related to function in the context of evolutionary conservation?

• Protein structure is not related to function in the context of evolutionary conservation.
• Evolutionary conservation has no impact on protein structure and function.
• Protein structure is related to function through evolutionary conservation of critical regions.
• Protein structure is only influenced by environmental factors, not evolutionary conservation.

What is a conservative substitution?

• A conservative substitution is a type of nucleotide substitution in DNA sequences.
• A conservative substitution is a type of substitution that always results in a loss of protein function.
• A conservative substitution is a type of mutation that leads to a complete change in protein structure.
• A conservative substitution is a type of amino acid substitution in which the new amino acid has similar chemical properties to the original amino acid, resulting in minimal impact on protein structure and function.

Which method is used to compare amino acid sequences for evolutionary studies?

• PCR analysis

• BLOSUM substitution matrix

• Gel electrophoresis

• DNA sequencing

What does a positive substitution score indicate in BLOSUM matrix?

• Conservation

• Negative selection

• No evolutionary relationship

• Error in analysis

Which domain is NOT a part of glutathione reductase?

• DNA-binding domain

• FAD-binding domain
• Interface domain

• NADPH-binding domain

The globin fold is preserved in proteins with how much sequence similarity

• Less than 10%

• 10-25%

•  26-50%

• Very little sequence similarity