ID Exam 2 Review 2024

SH presents to the pharmacy to pick up their meds after a weekend hiking trip. While there, they ask you about a strange rash they noticed since returning home. It is a circular red rash that has central clearing and looks like a bullseye. What is the most likely cause of this rash?

• Lyme disease

• Rocky Mountain Spotted Fever

• Anaplasmosis

• Tularemia

JW comes to the clinic after walking their dog in the woods of beautiful Western PA. Once home they noticed a tick in their armpit which was successfully removed with blunt forceps and antiseptic. They wonder if anything else can be done to prevent Lyme disease. What is the best treatment for JW at this time?

• Lyme vaccine

• Doxycycline 200mg po x 1 dose within 72hr of tick bite

• No further prophylaxis needed since tick removed

• 1. Doxycycline 100mg po q12hr for 14 days 

Which of the following is true regarding Rocky Mountain Spotted Fever?

• 1. We should wait for the results of both tests before initiating treatment 

• It is usually characterized by a maculopapular rash and flu/GI symptoms

• The proper treatment is doxycycline 100mg po/IV bid for 10 days

• 1. It is caused by the pathogen Francisella tularensis

What is true about viruses? (SATA)

• They have both DNA and RNA

• 1. They are unable to reproduce outside a living cell 

• 1. They have a complex organization 

• They are an obligate intracellular parasite

1. What is a function of the capsid?

• 1. It releases toxins 

• 1. It provides energy 

• Protects the genome

• 1. There is no function 

1. In which step of the life cycle are the genome copies and new viral proteins produced?

• Entry

• Attachment

• Assembly

• Replication

1. Where do most RNA viruses replicate?

• Endoplasmic reticulum

• Cytoplasm

• Mitochondria

• Nucleus

T/F: Negative-sense RNA viruses can directly translate their genome into viral proteins.

• true

• false

1. Which step in the life cycle does the JC virus kill cells?

• Attachment

• Replication

• Maturation

• Exit/release from the host cell

Which viral enzyme is correctly matched to its replication strategy?

• RNA-dependent RNA polymerase (RDRP) and positive sense RNA

• Reverse transcriptase and large DNA viruses

• Integrase and double-stranded RNA viruses

• 1. Thymidine kinase and negative sense RNA