DNA replication Review

DNA replication is the process by which a cell makes an identical copy of its __________.

The first step of DNA replication is the unwinding of the double helix structure by __________.

The enzyme responsible for synthesizing new DNA strands during replication is called DNA __________.

1. The synthesis of new DNA strands occurs in a ​ (a)   TO ​ (b)   direction.

• 5'
• 3'

1. The leading strand is synthesized ​ (a)   , while the lagging strand is synthesized ​ (b)   .

• continuously
• discontinuously

1. The short RNA sequences that initiate DNA synthesis are called __________.

The process of replacing RNA primers with DNA nucleotides is carried out by __________.

DNA replication is considered __________ because each resulting DNA molecule consists of one original strand and one newly synthesized strand.

First ​ (a)   ​ (b)   the DNA by ​ (c)   the ​ (d)   like a zip on a coat. The place where DNA replication is initiated is called the ​ (e)  

• DNA Helicase
• hydrogen bonds
• origin
• unwinds
• winds
• breaking
• building

Match the following

• Joins Okazaki fragments

• Ligase

• Unwinds/Breaks H-bonds linking the bases

• Helicase

• Adds RNA primer

• Topoisomerase

• Relieves supercoiling ahead of replication fork

• DNA Polymerase

• Synthesizes new DNA strand

• Primase