Innate immunity

What do lectins do

Answer explanation

Identify carbohydrates on microbial surfaces

PRR binds to PAMPs this leads to

Answer explanation

Phagocytosis

What are toll like receptors

Answer explanation

Single what and where the infection is. There’s many receptors for many ligands

Cytokines ….

Chemokines….

Nuerrophils….

Answer explanation

Regulate inflammation.

Direct immune cells to site of infection

.

Fights infection and forms myeloperxodase when it dies.

What’s the mechanism of nuerrophils

Answer explanation

Roll and bind

what’s anaphylatoxins

Answer explanation

Complement peptides such as C3A AND C5A

What do the complements C3a and C5a do

Answer explanation

Activate mats cells which increases vasoactive amines - histamine - cytokines. This attracts antibody’s

Name the main 3 inflammatory mediators

Answer explanation

Cytokines complements lipid mediators

Inflammatory mediator is released by….

Answer explanation

Mast cells

How is gene diversity maintained

Answer explanation

Gene rearrangement to make lots of receptors and clonal selection