Immunology Module 7

Transcription factor unique to B cells compared to T cells?

• myc

• NFAT

• NF-kB

• AP-1

The following can activate the B cells except:

• MHC class II

• Toll like receptors

• C3d

• Antigen

Which B cell activation mechanism is mediated by polysaccharides?

• T cell dependent

• T cell independent

• Both

• None of the above

Which B cell activation mechanism results in more isotype switching?

• T cell dependent

• T cell independent

• Both

• None of the above

Area in the peripheral lymph node where activated B cells are located.

• Follicle

• Parafollicular area

• Germinal center

• None of the above

The _________ is the enzyme involved in the recombination of the shift gene, responsible for isotype switching

Helper T cell subset involved in the survival of B cells with highest affinity resulting to affinity maturation

• Th1

• Th2

• Th17

• Tfh

Chemokine receptor seen expressed in activated B cells resulting to its migration towards the activated T cells?

• CCR7

• CXCR5

• CD40

• CD40L

Receptor for the regulation / inhibition of B cell response:

• FcγRIIB

• FcγRI

• FcγRIIIA

• FcεRI

Affinity maturation occurs in which part of the lymph nodes?

• Germinal center

• Follicles

• Parafollicular area

• None of the above