Genome Editing Technologies Quiz

Which of the following genome editing technologies involves a zinc finger and a FokI restriction enzymes?

• Zinc Finger Nucleases (ZFNs)

• Transcription Activator-Like Effector Nucleases (TALENs)

• CRISPR/Cas9

• RNA Interference (RNAi)

What is the primary mechanism by which TALENs recognize and target specific DNA sequences?

• Using sgRNA to bind to complementary DNA sequences

• Using zinc finger proteins to recognize specific DNA triplets

• Using TALE's that contain repeats to recognize single DNA base pairs

• Using RNA interference to degrade mRNA

Which genome editing technology is described as being highly efficient and relatively easy and inexpensive?

• Zinc Finger Nucleases (ZFNs)

• Transcription Activator-Like Effector Nucleases (TALENs)

• CRISPR/Cas9

• RNA Interference (RNAi)

Which two gene editing techniques make use of FokI to cut the DNA?

• ZFN only

• ZFN & TALEN

• TALEN & CRISPR

• CRISPR only

Which genome editing technology involves the use of a guide RNA (gRNA) and the Cas9 nuclease?

• Zinc Finger Nucleases (ZFNs)

• Transcription Activator-Like Effector Nucleases (TALENs)

• CRISPR/Cas9

• RNA Interference (RNAi)

What is a significant advantage of TALENs over ZFNs in terms of design?

• TALENs are more time-consuming to design.

• TALENs are able to recognise and attach ti the individual DNA bases.

• TALENs are less specific than ZFNs.

• TALENs are more expensive to design.

Which gene-editing technology is noted for its high efficiency and versatility but also has concerns about off-target effects?

• ZFNs

• TALENs

• CRISPR/Cas9

• None of the above

Which gene-editing technology was the first to be used in plant genetic modification and early therapeutic interventions?

• ZFNs

• TALENs

• CRISPR

• All of the above

Which statement is true about TALENs in the context of gene-editing technologies?

• TALENs are the easiest to use among the three technologies.

• TALENs are the 'version 2' of gene editing technologies.

• TALENs are widely used in agricultural biotechnology.

• TALENs are the most cost-effective technology.

Which genome editing technology was recognized by the Nobel Prize in Chemistry in 2020 which was awarded to Emmanuelle Charpentier and Jennifer Doudna.?

• ZFNs

• TALENs

• CRISPR

• RNAi