Therapeutics: Diuretic & fluid balance Thiazide Diretics (45-47)

Thiazides have a ceiling dose.

• True

• False

Answer explanation

meaning at a certain point, no matter how much the dose is increased, it will not work

Which diuretic is "stronger"?

• thiazide

• loop diuretic

Thiazides have shorter half lives than loops.

• True

• False

Answer explanation

thiazides have LONGER half lives than loops but are weaker diuretics

Select all of the clinical uses for thiazides

• edema or general volume overload

• hypertension

• kidney stones (hypercalciuria)

• diabetes insipidus (nephrogenic)

Where do thiazides work?

• A

• B

• C

Answer explanation

DCT

An ADR of thiazides is ___

• hypercalcemia

• hypocalcemia

Answer explanation

vs loops where an ADR is HYPOcalcemia. THis is starred

ADR for loops is hypocalcemia and for thiazides is hypercalcemia.

• True

• False

Select all of the ADRs for Thiazides

• hypokalemia

• hypovolemia

• hypercalcemia

• hyponatremia

• hypomagnesemia/hyperuricemia

Answer explanation

and sunburn

Select all of the thiazides.

• Chlrorothiazide (Diuril)

• Chlorthalidone (Thallitone)

• Hydrochlorothiazide

• Indapamide

• Metolazone (Zaroxolyn)

Which thiazide is the only one that can be PO and also IV?

• Chlrorothiazide (Diuril)

• Chlorthalidone (Thallitone)

• Hydrochlorothiazide

• Indapamide

• Metolazone (Zaroxolyn)

Answer explanation

all others are only PO