3.8 Clinical Trials Plenary

An adjuvant is a substance which makes the vaccine more ________, so enhancing the immune response.

The herd immunity _______ depends on the type of disease, the effectiveness of the vaccine and the density of the population.

Double-blind trial neither the subjects nor the researchers know which group subjects are in to prevent _______ interpretation of the results.

In a successful clinical trial there must be _______ significant differences between the groups.

Describe how participants in a clinical trial are randomly assigned into groups

• randomly assigned to control or treatment group

• Using a computer

• alphabetically by surname

• Taking into account characteristics such as age & gender

• either a treatment group or a placebo control group

Which feature of a clinical trial helps to establish reliable results of statistical significance?

• Single blind

• double blind

• random groups

• a placebo control group

• each group has a high number of participants

Which feature of a clinical trial helps to prevent biased interpretation of the results?

• Single blind

• double blind

• random groups

• a placebo control group

• each group has a high number of participants

Which feature of a clinical trial helps to ensure valid comparisons?

• Single blind

• double blind

• random groups

• a placebo control group

• each group has a high number of participants

Which feature of a clinical trial helps to o reduce bias in the distribution of characteristics?

• Single blind

• double blind

• random groups

• a placebo control group

• each group has a high number of participants

when analysing results between control group and treatment group. If the error bars ______ then there is not a statistical significance between the results.