Hematology Quiz

Hypersegmented neutrophils have six or more lobes and can be found in all of the following conditions EXCEPT:

• Megaloblastic anemia

• Chronic infection

• Liver disease

• Iron-deficiency anemia

Necrobiotic/apoptotic neutrophils are characterized by a pyknotic nucleus and can be occasionally found in normal smears and in:

• Chronic lymphocytic leukemia (CLL)

• Acute lymphoblastic leukemia (ALL)

• Acute myeloid leukemia (AML)

• Chronic myeloid leukemia (CML)

Neutrophilia is seen in all of the following conditions EXCEPT:

• Bacterial infections

• Stress

• Neutropenia

• Hemorrhage

What is a key finding in CLL?

• Smudge cells

• Auer rods

• Toxic granulation

• Hypersegmentation

Which abnormality can be artificially produced in the preparation of blood smears?

• Smudge cells

• Auer rods

• Döhle bodies

• Toxic granulation

Which disorder is characterized by excessive IgM production?

• Multiple myeloma

• Waldenström's macroglobulinemia

• Hairy cell leukemia

• CLL

Plasma cell leukemia is an aggressive variant of which condition?

• Multiple myeloma

• CLL

• AML

• ALL

Which of the following is associated with Waldenström's macroglobulinemia?

• Flame cells

• Dutcher bodies

• Lymphoplasmacytoid cells

• All of the above

What percentage of plasma cells in the peripheral blood defines plasma cell leukemia?

• 10%

• 15%

• 20%

• 25%

What is the primary site of involvement in hairy cell leukemia?

• Bone marrow

• Liver

• Spleen

• Lymph nodes