Biochemistry for Pharmaceutical Sciences II Quiz

What is the overall structure of an antibody protein?

• Primary and secondary structure

• Quaternary and tertiary structure

• Secondary and quaternary structure

• Primary and quaternary structure

What do antibodies recognize with high affinity and specificity?

• Lipids

• Antigens

• Carbohydrates

• Proteins

What role do antibodies serve as?

• Enzymes

• Hormones

• Therapeutic agents

• Structural proteins

Which bond is responsible for linking amino acids in a polypeptide chain?

• Peptide bond

• Hydrogen bond

• Ionic bond

• Covalent bond

What are the four levels of protein structure?

• Primary, Secondary, Tertiary, Quaternary

• Alpha, Beta, Gamma, Delta

• Linear, Circular, Spiral, Helical

• Simple, Complex, Advanced, Basic

What is the concept related to the interaction between proteins and other molecules?

• Binding affinity and binding specificity

• Molecular weight and density

• Thermal stability and solubility

• Electrical charge and polarity

What are monoclonal antibodies (mAbs) routinely used for in pharmaceuticals?

• As dietary supplements

• In agricultural pesticides

• In pharmaceutical research and as therapeutic agents

• As food preservatives

What is the primary characteristic of monoclonal antibodies?

• Produced from multiple B-lymphocyte clones

• Bind different epitopes

• Produced from a single B-lymphocyte clone and bind the same epitope

• Only treat cardiovascular disease

Which disease is NOT mentioned as being treated by monoclonal antibodies?

• Cancer

• Inflammatory disease

• Cardiovascular disease

• Diabetes

What was the first therapeutic monoclonal antibody approved in 1986?

• OKT3

• CD3

• mAb57

• Biosimilar10