Glutamate and Metabolism Quiz

Glutamate undergoes transamination to produce

• Alpha-ketoglutarate

• Oxaloacetate

• Alanine

• More than one of the above

Glutamate requires ____ to undergo reductive amination

• FAD

• NAD+

• NADH

• NADP+

• NH3

_____ is the enzyme that converts glutamate to glutamine using ADP

• Glutamine synthetase

• Transaminase

• Glutamate Dehydrogenase

• Aminotransferase

• Glutaminase

Futile Cycles pointlessly hydrolyze ___

• NADH

• GTP

• ATP

• ADP

• NAD+

Aspartate can undergo

• Hydrolysis

• Transamination

• Reductive amination

• More than one of the above

Which of the following is FALSE?

• Methionine uses ATP to get converted into S-Adenosyl-methionine

• S-Adenosyl-homocysteine gets converted to homocysteine

• cystathionine gets converted to homocysteine

• cystathionine finally gets converted to cysteine and alpha-ketobutyrate

Which of the following is FALSE?

• Processed Tg is exocytosed from follicular space

• Iodide is actively transported out of thyrocytes

• Oxidation of iodide by peroxidase forms iodinimum ion for electrophilib sub

• Thyroglobulin is proteolyzed to form T3 and T4

Which of the following steps is correctly numbered in the T3 and T4 synthesis and release pathway?

• Na/Iodide symporter

• Tg secretion

• exocytosis of Tg

• oxidation of iodide

Which of the following is FALSE?

• T4 is formed from T3 by a peripheral deiodinase

• T3 binds to transcription factors

• T3 increases our basal metabolic rate

• thyroid hormones are not absolutely necessary for life

Which of the following amino acids are paired incorrectly with the neurotransmitters they convert into?

• Serotonin from tryptophan

• GABA from tryptophan

• Dihydroxyphenylalanine from phenylalanine

• More than two of the above