de Soto's Long March

Match the following vocabulary words with their definitions

• protective covering

• Disease

• first person to settle in a region

• Exploit

• sickness

• Smallpox

• a serious disease that spreads

• Pioneer

• to take unfair advantage of a person

• Armor

Why is the Mississippi River the most important river in the United States?

• It flows almost the entire length of the United States.

• It is the prettiest river in the United States.

• All gold and silver is located in the river.

Why might de Soto have considered his expedition a failure?

Name 5 states that de Soto explored in North America

Some European explorers in North America soon began to __________ the Native Americans

Spanish explorers wore _______ when fighting the Native Americans.

Many Native Americans died from ___________ after contact with the European explorers.