Calibration method

Which of the following is a primary purpose of calibration in analytical chemistry?

• To adjust the instrument settings

• To verify the accuracy of measurement

• To improve sample quality

• To reduce the cost of analysis

The method in which a known quantity of analyte is added directly to the sample to account for matrix effects is called:

• Standard addition

• External calibration

• Internal calibration

• Blank calibration

Which of the following methods uses a reference compound added in constant quantity to all standards and samples for calibration?

• External calibration

• Internal standard method

• Matrix-matched calibration

• Response factor calibration

In external calibration, what is plotted to obtain the calibration curve?

• Instrument response vs time

• Instrument response vs concentration

• Time vs concentration

• Instrument response vs analyte type

In the internal standard method, the ratio of the analyte’s response to the internal standard’s response is plotted against:

• Time

• Concentration of the internal standard

• Concentration of the analyte

• Volume of the sample

In the standard addition method, how is the original concentration of the analyte calculated?

• From the intercept of the calibration curve

• From the slope of the calibration curve

• From the average response of the sample

• From the maximum response obtained