Complement Cascade Quiz

What is the initial complex formed in the complement cascade?

• C1 complex

• C3 convertase

• C5b-9 complex

• C3b and C3a fragments

Which pathway is involved in the formation of the C3 convertase?

• Classical pathway

• Alternative pathway

• Both Classical and Alternative pathways

• Neither pathway

What fragments are produced during C3 hydrolysis?

• C3b and C3a fragments

• C5a and C5b fragments

• C2a and C4b fragments

• C6 and C7 fragments

What does C3b cleave to form C5a and C5b?

• C5

• C3

• C4

• C2

Which components form the cylindrical membrane attack complex?

• C5b, C6, C7, C8, and C9

• C1, C2, C3, and C4

• C3a, C3b, and C5a

• C2a, C4b, and C3b

What happens to the cell at the end of the complement cascade?

• It swells and bursts

• It shrinks and dies

• It divides

• It becomes dormant

Which antibody is involved in the formation of the C1 complex?

• IgG

• IgA

• IgM

• IgE

What is the role of C3 convertase in the complement cascade?

• It hydrolyzes C3

• It forms the C1 complex

• It cleaves C5

• It forms the membrane attack complex

Which fragments are involved in the classical pathway?

• C2a and C4b

• C5a and C5b

• C3b and C3a

• C6 and C7

What is the function of the membrane attack complex?

• To lyse the target cell

• To bind antigens

• To activate antibodies

• To inhibit cell division