DNA replication

DNA replication

University

10 Qs

quiz-placeholder

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DNA replication

DNA replication

Assessment

Quiz

Biology

University

Medium

Created by

Jen Kit Tan

Used 3+ times

FREE Resource

10 questions

Show all answers

1.

MULTIPLE CHOICE QUESTION

1 min • 1 pt

Which of the following is a key difference between leading and lagging strand synthesis during DNA replication?

Leading strand is synthesized in fragments, lagging strand continuously.

Leading strand requires RNA primers, lagging strand does not.

Leading strand is synthesized continuously, lagging strand in Okazaki fragments.

Both are synthesized discontinuously.

2.

MULTIPLE CHOICE QUESTION

1 min • 1 pt

Which enzyme is responsible for unwinding the DNA double helix during replication?

DNA polymerase

Primase

Helicase

Exonuclease

3.

MULTIPLE CHOICE QUESTION

1 min • 1 pt

What role does the enzyme primase play in DNA replication?

Synthesizes DNA strands

Synthesizes RNA primers

Joins Okazaki fragments

Repairs mismatched nucleotides

4.

MULTIPLE CHOICE QUESTION

1 min • 1 pt

Which of the following enzymes relieves the tension created ahead of the replication fork during DNA replication?

DNA polymerase

Helicase

Topoisomerase

DNA ligase

5.

MULTIPLE CHOICE QUESTION

1 min • 1 pt

How does cisplatin inhibit DNA replication in cancer cells?

Inhibits DNA polymerase directly

Causes the formation of interstrand and intrastrand cross-links in DNA

Prevents helicase from unwinding DNA

Inhibits topoisomerase I activity

6.

MULTIPLE CHOICE QUESTION

1 min • 1 pt

What is the primary mechanism of action of topoisomerase inhibitors in cancer therapy?

Prevents the initiation of DNA replication by inhibiting helicase

Inhibits DNA polymerase, halting DNA strand elongation

Stabilizes the DNA-topoisomerase complex, leading to double-strand DNA breaks

Prevents DNA strand separation by inhibiting primase activity

7.

MULTIPLE CHOICE QUESTION

1 min • 1 pt

What type of mutation occurs when a single nucleotide substitution results in the premature formation of a stop codon?

Missense mutation

Nonsense mutation

Silent mutation

Frameshift mutation

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