Which of the following is a key difference between leading and lagging strand synthesis during DNA replication?

DNA replication

Quiz
•
Biology
•
University
•
Medium
Jen Kit Tan
Used 3+ times
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10 questions
Show all answers
1.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
Leading strand is synthesized in fragments, lagging strand continuously.
Leading strand requires RNA primers, lagging strand does not.
Leading strand is synthesized continuously, lagging strand in Okazaki fragments.
Both are synthesized discontinuously.
2.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
Which enzyme is responsible for unwinding the DNA double helix during replication?
DNA polymerase
Primase
Helicase
Exonuclease
3.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
What role does the enzyme primase play in DNA replication?
Synthesizes DNA strands
Synthesizes RNA primers
Joins Okazaki fragments
Repairs mismatched nucleotides
4.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
Which of the following enzymes relieves the tension created ahead of the replication fork during DNA replication?
DNA polymerase
Helicase
Topoisomerase
DNA ligase
5.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
How does cisplatin inhibit DNA replication in cancer cells?
Inhibits DNA polymerase directly
Causes the formation of interstrand and intrastrand cross-links in DNA
Prevents helicase from unwinding DNA
Inhibits topoisomerase I activity
6.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
What is the primary mechanism of action of topoisomerase inhibitors in cancer therapy?
Prevents the initiation of DNA replication by inhibiting helicase
Inhibits DNA polymerase, halting DNA strand elongation
Stabilizes the DNA-topoisomerase complex, leading to double-strand DNA breaks
Prevents DNA strand separation by inhibiting primase activity
7.
MULTIPLE CHOICE QUESTION
1 min • 1 pt
What type of mutation occurs when a single nucleotide substitution results in the premature formation of a stop codon?
Missense mutation
Nonsense mutation
Silent mutation
Frameshift mutation
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