DNA Replication Notes

What is the role of DNA polymerase in DNA replication?

• It synthesizes new DNA strands by adding nucleotides.

• It prevents the DNA strands from rejoining.

• It seals the gaps between Okazaki fragments.

• It unwinds the DNA double helix.

Which enzyme is responsible for unwinding the DNA double helix?

• Topoisomerase

• Helicase

• Primase

• DNA ligase

What is the function of primase in DNA replication?

• It prevents supercoiling of DNA.

• It removes RNA primers.

• It adds nucleotides to the growing DNA strand.

• It synthesizes RNA primers.

What are Okazaki fragments?

• Short DNA sequences that prevent DNA from rewinding.

• Short DNA sequences synthesized on the leading strand.

• Short RNA sequences synthesized by primase.

• Short DNA sequences synthesized on the lagging strand.

Which enzyme replaces RNA primers with DNA?

• Topoisomerase

• Helicase

• DNA polymerase III

• DNA polymerase I

What is the role of single-strand binding proteins?

• They replace RNA primers with DNA.

• They prevent the DNA strands from rejoining.

• They unwind the DNA double helix.

• They synthesize new DNA strands.

What is the main difference between leading and lagging strands?

• Leading strand is synthesized continuously, lagging strand is synthesized in fragments.

• Leading strand is synthesized in fragments, lagging strand is synthesized continuously.

• Both strands are synthesized continuously.

• Both strands are synthesized in fragments.

What is the function of topoisomerase during DNA replication?

• It adds nucleotides to the growing DNA strand.

• It seals the gaps between Okazaki fragments.

• It synthesizes RNA primers.

• It prevents supercoiling of DNA.