Difficult Biochemistry MCQs on Heteropolysaccharides

Which of the following heteropolysaccharides is a major component of connective tissue?

• Hyaluronic acid

• Chitin

• Cellulose

• Amylopectin

Chondroitin sulfate is primarily composed of which repeating disaccharide unit?

• Glucose and galactose

• Glucuronic acid and N-acetylgalactosamine

• N-acetylglucosamine and mannose

• Glucose and fructose

Which enzyme is responsible for the degradation of heparan sulfate?

• Hyaluronidase

• Heparinase

• Chitinase

• Glucuronidase

Which of the following is true about glycosaminoglycans (GAGs)?

• They are always branched polysaccharides.

• They contain a high degree of sulfation.

• They are primarily found in the cytosol.

• They have no role in water retention.

Keratan sulfate is unique among glycosaminoglycans because it:

• Lacks uronic acid.

• Contains glucuronic acid.

• Is non-sulfated.

• Is only found in bacteria.

Heparin is synthesized predominantly in which type of cells?

• Neurons

• Hepatocytes

• Mast cells

• Osteoblasts

Which of the following is the primary function of hyaluronic acid in tissues?

• Structural support

• Inhibition of clotting

• Providing lubrication

• Degradation of toxins

The main repeating disaccharide in dermatan sulfate is:

• Glucuronic acid and N-acetylglucosamine

• L-iduronic acid and N-acetylgalactosamine

• Mannose and galactose

• Heparin sulfate

Which heteropolysaccharide is most abundant in the extracellular matrix of the skin?

• Heparin

• Chondroitin sulfate

• Hyaluronic acid

• Keratan sulfate

Which structural characteristic of heparin is responsible for its anticoagulant properties?

• High sulfate content

• Low molecular weight

• Beta 1,4 linkages

• Absence of glucuronic acid