Exploring DNA: Structure and Mutations

What is the shape of the DNA molecule?

• Linear

• Double helix

• Circular

• Zigzag

Which of the following base pairs is correct according to the base pairing rules?

• Adenine - Cytosine

• Guanine - Thymine

• Adenine - Thymine

• Cytosine - Thymine

During DNA replication, which enzyme is responsible for unwinding the DNA double helix?

• DNA polymerase

• Helicase

• Ligase

• Primase

What is the role of DNA polymerase in DNA replication?

• Unwinds the DNA strand

• Joins Okazaki fragments

• Synthesizes new DNA strands

• Adds RNA primers

Which of the following is a type of point mutation?

• Inversion

• Deletion

• Substitution

• Duplication

Tags

NGSS.HS-LS3-2

What is the complementary strand for the DNA sequence 5'-ATCG-3'?

• 5'-TAGC-3'

• 3'-TAGC-5'

• 5'-CGAT-3'

• 3'-CGAT-5'

Which of the following mutations is likely to have the most significant effect on a protein?

• Silent mutation

• Missense mutation

• Nonsense mutation

• Neutral mutation

How does a frameshift mutation affect the reading frame of a gene?

• It does not affect the reading frame.

• It shifts the reading frame, altering the entire amino acid sequence downstream.

• It only affects the first codon.

• It replaces one amino acid with another.

Tags

NGSS.HS-LS3-2

Predict the effect of a substitution mutation that changes a codon from UUU to UUC.

• It will result in a frameshift mutation.

• It will cause a nonsense mutation.

• It will have no effect on the protein (silent mutation).

• It will change the protein structure significantly.

Tags

NGSS.HS-LS3-2

Analyze the impact of a deletion mutation in a gene coding for an enzyme.

• The enzyme will be produced normally.

• The enzyme will be produced but with altered function.

• The enzyme will not be produced at all.

• The enzyme will be produced with enhanced function.

Tags

NGSS.HS-LS3-2

NGSS.HS-LS1-1